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James Cameron's Avatar: The Way of Water led ticket sales in movie theaters for the sixth straight weekend, making it the first film to have such a reign atop the box office since 2009's Avatar.

The San Francisco 49ers quarterback Brock Purdy went on a journey from "Mr. Irrelevant" to football superstar.

New York City public school students are going back to school Monday, but parents and educators are bracing themselves as COVID-19 infections continue to rise among children.

Britain and the European Union signed a new agreement to solve one of Brexit's thorniest challenges: the trading status of Northern Ireland.

Treasury Secretary Janet Yellen made a surprise visit to Ukraine and announced $1.25 billion in economic aid as the country's war with Russia goes into its second year.

An All Nippon Airways (ANA) plane was forced to make an emergency landing on Wednesday because of an apparent electrical failure. ANA and Japan Airlines have grounded all their 787s in response. Later Wednesday, the FAA grounded the U.S. fleet, which effectively grounds all 787s.

The U.S. intelligence community concludes it's "very unlikely" a foreign country is responsible for the so-called Havana Syndrome ailments involving U.S. officials working abroad.

Chicago Mayor Lori Lightfoot's first term in office saw a spike in crime, disputes with labor unions, and the pandemic. She's running for reelection next week — against eight challengers.

NPR's Michel Martin speaks with Turkey correspondent for The Economist, Piotr Zalewski, about the political implications in the aftermath of the earthquake there.

Iran has jailed up to 20,000 people in months of protests against the regime. The announcement that it's pardoning prisoners is an empty gesture, a human rights lawyer says.